A specific vitamin: Niacin
The emergence of niacin as a specific vitamin dates back to the 1930s, but it has been known to the chemists as a substance called nicotinic acid for well over a hundred years. The vitamin occurs both as nicotinic acid (the acid) or nicotinamide (the amide), and these are the two specific names which come under the generic, or family title, of niacin. Occasionally it is written, incorrectly, as B3 and in the U.S.A. the generic term niacin is sometimes used to describe the acid form of the vitamin.
Another name for niacin found in older books on nutrition is ‘vitamin PP‘. This refers to the deficiency disease, pellagra. Niacin was found to protect against pellagra and was accordingly described as the pellagra- prevention factor, hence PP. This term is no longer in use but it does help in remembering a little of the history of this B vitamin. Pellagra is a skin disease which affects communities which live on maize as their main source of food with little or no protein foods to supplement the diet. Typical symptoms are severe dermatitis and reddening of the skin. It is summed up in textbooks as the disease of the three D’s — dementia, diarrhoea and dermatitis, but this is rather a sweeping description and can cover effects in many other deficiency diseases and illnesses. Read the rest of this entry »
