Menstrual Cycle and Disease, Vital Medication and Hormones levels
The variation in hormones levels over the cycle causes far-reaching effects throughout the body. For instance, hormones can affect the way that women’s bodies process drugs. Sometimes women with epilepsy will have a seizure just before or during the first days of their period, something called catamenial epilepsy. This is not just variation in the condition across a cycle as used to be thought, but also a reflection of the fact that many anti-epileptic drugs are metabolized through an enzyme pathway called CYP 3A4. The activity of this system is accelerated by progesterone in the second half of the cycle, so that drugs are cleared more quickly from the body and may be temporarily less effective in preventing fits. Read the rest of this entry »
